Tbc1d30em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Tbc1d30em1(IMPC)J |
Name: |
TBC1 domain family, member 30; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:5790099 |
Synonyms: |
Tbc1d30em1J |
Gene: |
Tbc1d30 Location: Chr10:121099725-121187183 bp, - strand Genetic Position: Chr10, 69.12 cM, cytoband D3
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Alliance: |
Tbc1d30em1(IMPC)J page
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IMPC: |
Tbc1d30 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele from project Tbc1d30-7955J-M6512 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TTGTGTATGTTCTCTGGAAA, ATTGCGTTCCCAGAAGTGTT, TTGGTTTCTGACGCATCAGG and TGGGCATATTAAAATCCTGG, which resulted in a 349 bp deletion beginning at Chromosome 10 negative strand position 121,297,003bp CATCAGGAGGAACTTTGGTC, and ending after CTATTGCGTTCCCAGAAGTG at 121,296,655bp (GRCm38/mm10). This mutation deletes exon 6 and 180 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 199 and early truncation 29 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
3 reference(s) |
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