Pla2g12b^mpc96H
Chemically induced Allele Detail

Summary

• Symbol: Pla2g12b^mpc96H
• Name: phospholipase A2, group XIIB; muta-ped-c3pde 96, Harwell
• MGI ID: MGI:5791984
• Gene: Pla2g12b Location: Chr10:59239482-59257798 bp, + strand Genetic Position: Chr10, 29.54 cM, cytoband B3
• Alliance: Pla2g12b^mpc96H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A point mutation that results in the amino acid substitution of aspartic acid for tyrosine at position 66 (Y66N). (J:234901)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pla2g12b Mutation: 17 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)