Wars2^mpc151H
Chemically induced Allele Detail

Summary

• Symbol: Wars2^mpc151H
• Name: tryptophanyl tRNA synthetase 2 (mitochondrial); muta-ped-c3pde 151, Harwell
• MGI ID: MGI:5791998
• Synonyms: Wars2^V117L
• Gene: Wars2 Location: Chr3:99047423-99128546 bp, + strand Genetic Position: Chr3, 43.03 cM, cytoband F3
• Alliance: Wars2^mpc151H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to T point mutation that results in the amino acid substitution of leucine for valine at position 117 (V117L). (J:234901)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wars2 Mutation: 22 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 3 reference(s)