Clrn2^mpc169H
Chemically induced Allele Detail

Summary

• Symbol: Clrn2^mpc169H
• Name: clarin 2; muta-ped-c3pde 169, Harwell
• MGI ID: MGI:5792002
• Synonyms: Clrn2^clarinet, Clrn2^p.Trp4*
• Gene: Clrn2 Location: Chr5:45611093-45621491 bp, + strand Genetic Position: Chr5, Syntenic
• Alliance: Clrn2^mpc169H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis produced a non-synonymous G-to-A transition at nucleotide 11 (ENSMUST00000053250) to substitute tryptophan with a stop codon at position 4 (Trp4*). (J:283627)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clrn2 Mutation: 26 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 2 reference(s)