Loxhd1^mpc188H
Chemically induced Allele Detail

Summary

• Symbol: Loxhd1^mpc188H
• Name: lipoxygenase homology domains 1; muta-ped-c3pde 188, Harwell
• MGI ID: MGI:5792020
• Gene: Loxhd1 Location: Chr18:77369654-77530626 bp, + strand Genetic Position: Chr18, 52.2 cM
• Alliance: Loxhd1^mpc188H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced two point mutations (c.4370T>A and c.5323A>G) that result in the amino acid substitutions of isoleucine with asparagine at position 1457 (p.I1457N) and threonine with alanine at position 1775 (p.T1775A). (J:234901)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Loxhd1 Mutation: 104 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)