Chrm3^mpc214H
Chemically induced Allele Detail

Summary

• Symbol: Chrm3^mpc214H
• Name: cholinergic receptor, muscarinic 3, cardiac; muta-ped-c3pde 214, Harwell
• MGI ID: MGI:5792039
• Gene: Chrm3 Location: Chr13:9925522-10410883 bp, - strand Genetic Position: Chr13, 3.72 cM
• Alliance: Chrm3^mpc214H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A point mutation that results in the amino acid substitution of a termination codon for leucine at position 12 (L12*). (J:234901)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chrm3 Mutation: 51 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)