Acan^mpc227H
Chemically induced Allele Detail

Summary

• Symbol: Acan^mpc227H
• Name: aggrecan; muta-ped-c3pde 227, Harwell
• MGI ID: MGI:5792073
• Synonyms: Acan^A1946V
• Gene: Acan Location: Chr7:78703231-78764847 bp, + strand Genetic Position: Chr7, 44.88 cM
• Alliance: Acan^mpc227H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to T point mutation that results in the amino acid substitution of valine for alanine at position 1946 (A1946V). (J:234901)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Acan Mutation: 80 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)