Hars1^mpc231H
Chemically induced Allele Detail

Summary

• Symbol: Hars1^mpc231H
• Name: histidyl-tRNA synthetase 1; muta-ped-c3pde 231, Harwell
• MGI ID: MGI:5792078
• Gene: Hars1 Location: Chr18:36899581-36916258 bp, - strand Genetic Position: Chr18, 19.46 cM, cytoband B3
• Alliance: Hars1^mpc231H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C point mutation that results in the amino acid substitution of proline for serine at position 111 (S111P). (J:234901)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hars1 Mutation: 27 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)