Pcsk1^mpc242H
Chemically induced Allele Detail

Summary

• Symbol: Pcsk1^mpc242H
• Name: proprotein convertase subtilisin/kexin type 1; muta-ped-c3pde 242, Harwell
• MGI ID: MGI:5792086
• Gene: Pcsk1 Location: Chr13:75237945-75282980 bp, + strand Genetic Position: Chr13, 40.63 cM, cytoband C2
• Alliance: Pcsk1^mpc242H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to T point mutation that results in the amino acid substitution of leucine for valine at position 96 (V96L). (J:234901)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcsk1 Mutation: 50 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 2 reference(s)