Hdac6tm1Anfi
Targeted Allele Detail
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| Symbol: |
Hdac6tm1Anfi |
| Name: |
histone deacetylase 6; targeted mutation 1, Andre Fischer |
| MGI ID: |
MGI:5792141 |
| Gene: |
Hdac6 Location: ChrX:7796359-7814128 bp, - strand Genetic Position: ChrX, 3.58 cM
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| Alliance: |
Hdac6tm1Anfi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:234763
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: A neomycin resistance gene replaced exons 10-13. Semi-quantitative PCR and immunoblot analysis confirmed absence of mRNA and protein levels in the hippocampus and cortex of homozygotes.
(J:234763)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Hdac6 Mutation: |
17 strains or lines available
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| Original: |
J:234763 Govindarajan N, et al., Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease. EMBO Mol Med. 2013 Jan;5(1):52-63 |
| All: |
1 reference(s) |
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Analysis Tools
