Snrk^tm1Rra
Targeted Allele Detail

Summary

• Symbol: Snrk^tm1Rra
• Name: SNF related kinase; targeted mutation 1, Ramani Ramchandran
• MGI ID: MGI:5792702
• Gene: Snrk Location: Chr9:121946332-121998768 bp, + strand Genetic Position: Chr9, 72.89 cM
• Alliance: Snrk^tm1Rra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218247
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exon 3. Western blot analysis confirmed the absence of protein expression in the heart. (J:218247)

Expression

In Mice Carrying this Mutation:	67 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snrk Mutation: 37 strains or lines available

References

• Original: J:218247 Cossette SM, et al., Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Biol Open. 2014;4(1):48-61
• All: 2 reference(s)