Dusp3^tm1Srah
Targeted Allele Detail

Summary

• Symbol: Dusp3^tm1Srah
• Name: dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related); targeted mutation 1, Souad Rahmouni
• MGI ID: MGI:5792725
• Gene: Dusp3 Location: Chr11:101861969-101877839 bp, - strand Genetic Position: Chr11, 65.48 cM, cytoband D
• Alliance: Dusp3^tm1Srah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235051
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exon 2. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:235051)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dusp3 Mutation: 24 strains or lines available

References

• Original: J:235051 Amand M, et al., DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase. Mol Cancer. 2014;13:108
• All: 5 reference(s)