Ctnnbl1^tm1.2Crad
Targeted Allele Detail

Summary

• Symbol: Ctnnbl1^tm1.2Crad
• Name: catenin, beta like 1; targeted mutation 1.2, Cristina Rada
• MGI ID: MGI:5795695
• Synonyms: Ctnnbl1^deltaE3
• Gene: Ctnnbl1 Location: Chr2:157579321-157733534 bp, + strand Genetic Position: Chr2, 78.4 cM, cytoband H2
• Alliance: Ctnnbl1^tm1.2Crad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232010
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked beta-galactosidase/neomycin resistance gene was inserted upstream of a floxed exon 3. Flp-mediated recombination removed the reporter/selection cassette. Cre-mediated recombination removed exon 3. (J:232010)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctnnbl1 Mutation: 37 strains or lines available

References

• Original: J:232010 Chandra A, et al., Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice. Cell Cycle. 2013 Mar 1;12(5):732-42
• All: 1 reference(s)