Icostm2b(EUCOMM)Wtsi
Targeted Allele Detail
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Symbol: |
Icostm2b(EUCOMM)Wtsi |
Name: |
inducible T cell co-stimulator; targeted mutation 2b, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5804645 |
Gene: |
Icos Location: Chr1:61017086-61039479 bp, + strand Genetic Position: Chr1, 30.6 cM
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Alliance: |
Icostm2b(EUCOMM)Wtsi page
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IMPC: |
Icos gene page |
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Mutant Cell Line: |
EPD0912_4_C07 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204739
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: Cre-mediated excision of the parental Icostm2a(EUCOMM)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:204739)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Icos Mutation: |
36 strains or lines available
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Original: |
J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023; |
All: |
2 reference(s) |
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