Tg(Gata4*G2-cre)#Roja
Transgene Detail

Summary

• Symbol: Tg(Gata4*G2-cre)#Roja
• Name: transgene insertion, Anabel Rojas
• MGI ID: MGI:5805214
• Synonyms: G2-GATA4^Cre, Gata4-G2-Cre
• Transgene: Tg(Gata4*G2-cre)#Roja Location: unknown
• Alliance: Tg(Gata4*G2-cre)#Roja page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Gata4*G2-cre)#Roja expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gata4 (MGI:95664)

• Mutation details: A transgene consisting of an 817 bp fragment containin the conserved region, CR2, of the G2 Gata4 enhancer, 642 bp fragment containing minimal promoter from the mouse Mef2c gene, the cre cDNA, and SV40 splice and polyA signal sequence was generated. A total of 4 founder lines with similar patterns of cre activity were created. Line numbers were not specified in the original reference. (J:231985)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gata4 (mouse) Summary of all recombinase alleles driven by Gata4. Comparative matrix view of recombinase activities Alliance mouse Gata4 gene page

Disease models

Expression

In Mice Carrying this Mutation:

28 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:231985 Delgado I, et al., GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice. Hepatology. 2014 Jun;59(6):2358-70
• All: 8 reference(s)