Pcdha9^em1Clo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pcdha9^em1Clo
• Name: protocadherin alpha 9; endonuclease-mediated mutation 1, Cecilia Lo
• MGI ID: MGI:5805231
• Gene: Pcdha9 Location: Chr18:37130933-37320710 bp, + strand Genetic Position: Chr18, 19.46 cM
• Alliance: Pcdha9^em1Clo page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutations: Intragenic deletion, Nucleotide substitutions
• Mutation details: CRISPR/Cas9 and a donor sequence were used to generate this allele, which has the aspartic acid at residue 796 replaced with valine and the leucine and methionine at amino acids 797 and 798 deleted. (J:242757)
• Inheritance: Not Specified

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdha9 Mutation: 45 strains or lines available

References

• Original: J:242757 Liu X, et al., The complex genetics of hypoplastic left heart syndrome. Nat Genet. 2017 Jul;49(7):1152-1159
• All: 1 reference(s)