Faf2^tm1Tfji
Targeted Allele Detail

Summary

• Symbol: Faf2^tm1Tfji
• Name: Fas associated factor family member 2; targeted mutation 1, Toyoshi Fujimoto
• MGI ID: MGI:5805286
• Synonyms: Ubxd8^flox
• Gene: Faf2 Location: Chr13:54769597-54811876 bp, + strand Genetic Position: Chr13, 28.88 cM
• Alliance: Faf2^tm1Tfji page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235325
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 1. (J:235325)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Faf2 Mutation: 24 strains or lines available

References

• Original: J:235325 Imai N, et al., Hepatocyte-Specific Depletion of UBXD8 Induces Periportal Steatosis in Mice Fed a High-Fat Diet. PLoS One. 2015;10(5):e0127114
• All: 4 reference(s)