Atg13^{tm2b(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Atg13^{tm2b(EUCOMM)Hmgu}
• Name: autophagy related 13; targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5805683
• Gene: Atg13 Location: Chr2:91504963-91540921 bp, - strand Genetic Position: Chr2, 50.63 cM
• Alliance: Atg13^{tm2b(EUCOMM)Hmgu} page
• IMPC: Atg13 gene page

Mutation origin

• Mutant Cell Line: HEPD0797_7_E11
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8A3.N1.C2 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Atg13^{tm2a(EUCOMM)Hmgu} allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Expression

In Mice Carrying this Mutation:	48 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg13 Mutation: 135 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 3 reference(s)