Tg^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tg^m1Btlr
• Name: thyroglobulin; mutation 1, Bruce Beutler
• MGI ID: MGI:5806301
• Synonyms: ito
• Gene: Tg Location: Chr15:66542606-66722570 bp, + strand Genetic Position: Chr15, 29.3 cM, cytoband D3-E
• Alliance: Tg^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 66,766,162 (v38) on chromosome 15, or base pair 95,407 in the GenBank genomic region NC_000081. The mutation corresponds to residue 6,845 in the NM_009375 mRNA sequence in exon 39 of 48 total exons. The mutation results in substitution of glutamine 2,275 to a premature stop codon (Q2275*) in the protein. (J:236668)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tg Mutation: 147 strains or lines available

References

• Original: J:236668 Turer E, et al., Mutagenetix entry for ito. MGI Direct Data Submission. 2016
• All: 1 reference(s)