Rac2^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rac2^m3Btlr
• Name: Rac family small GTPase 2; mutation 3, Bruce Beutler
• MGI ID: MGI:5806333
• Synonyms: potter
• Gene: Rac2 Location: Chr15:78443369-78456983 bp, - strand Genetic Position: Chr15, 37.57 cM
• Alliance: Rac2^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to A transversion at base pair 78,570,743 (v38) on chromosome 15, or base pair 2,041 in the GenBank genomic region NC_000081. The mutation corresponds to residue 234 in the mRNA sequence NM_009008 within exon 2 of 7 total exons. The mutation results in substitution of tyrosine 32 for a premature stop codon (Y32*) in the protein. (J:236680)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rac2 Mutation: 17 strains or lines available

References

• Original: J:236680 Choi JH, et al., Mutagenetix entry for potter. MGI Direct Data Submission. 2016
• All: 1 reference(s)