Slx4^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slx4^m1Btlr
• Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); mutation 1, Bruce Beutler
• MGI ID: MGI:5806336
• Synonyms: slim
• Gene: Slx4 Location: Chr16:3796969-3821634 bp, - strand Genetic Position: Chr16, 2.34 cM
• Alliance: Slx4^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 3,990,910 (v38) on chromosome 16, or base pair 12,920 in the GenBank genomic region NC_000082. The mutation corresponds to residue 1,473 in the NM_177472 mRNA sequence in exon 7 of 15 total exons. The mutation results in substitution of glutamine (Q) 389 for a premature stop codon (Q389*) in the protein. (J:236683)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slx4 Mutation: 57 strains or lines available

References

• Original: J:236683 Chen Z, et al., Mutagenetix entry for slim. MGI Direct Data Submission. 2016
• All: 1 reference(s)