Itgax^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Itgax^M1Btlr
• Name: integrin alpha X; mutation 1, Bruce Beutler
• MGI ID: MGI:5806337
• Synonyms: Adendritic
• Gene: Itgax Location: Chr7:127728719-127749829 bp, + strand Genetic Position: Chr7, 69.98 cM
• Alliance: Itgax^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to A transversion at base pair 128,148,572 (v38) on chromosome 7, or base pair 19,044 in the GenBank genomic region NC_000073. The mutation corresponds to residue 3,211 in the mRNA sequence NM_021334 within exon 27 of 30 total exons. The mutation results in substitution of tyrosine 1053 (Y1053) to a premature stop codon (Y1053*) in the protein. (J:236684)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Itgax Mutation: 76 strains or lines available

References

• Original: J:236684 Zeng M, et al., Mutagenetix entry for Adendritic. MGI Direct Data Submission. 2016
• All: 1 reference(s)