Dock2^m6Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dock2^m6Btlr
• Name: dedicator of cyto-kinesis 2; mutation 6, Bruce Beutler
• MGI ID: MGI:5806434
• Synonyms: capitol_reef
• Gene: Dock2 Location: Chr11:34176815-34674719 bp, - strand Genetic Position: Chr11, 19.68 cM, cytoband A5
• Alliance: Dock2^m6Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to C transversion at base pair 34,294,170 (v38) on chromosome 11, or base pair 489,723 in the GenBank genomic region NC_000077 within the acceptor splice site of intron 31. The effect of the mutation at the cDNA and protein levels have not examined, but the mutation is predicted to result in an in-frame skipping of the 59-nucleotide exon 32 (out of 52 total exons). (J:236689)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock2 Mutation: 143 strains or lines available

References

• Original: J:236689 Yue T, et al., Mutagenetix entry for capitol_reef. MGI Direct Data Submission. 2016
• All: 1 reference(s)