Pik3cd^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pik3cd^m2Btlr
• Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; mutation 2, Bruce Beutler
• MGI ID: MGI:5806440
• Synonyms: grand_tetons
• Gene: Pik3cd Location: Chr4:149733625-149787023 bp, - strand Genetic Position: Chr4, 80.15 cM
• Alliance: Pik3cd^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 149,652,699 (v38) on chromosome 4, or base pair 49,868 in the GenBank genomic region NC_000070. The mutation corresponds to residue 2,917 in the mRNA sequence NM_001029837 within exon 20 of 23 total exons. The mutation results in a leucine (L) to proline (P) substitution at position 880 (L880P) in all isoforms. (J:236693)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pik3cd Mutation: 45 strains or lines available

References

• Original: J:236693 Zeng M, et al., Mutagenetix entry for grand_tetons. MGI Direct Data Submission. 2016
• All: 1 reference(s)