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Ifngr1m1Btlr
Chemically induced Allele Detail
Summary
Symbol: Ifngr1m1Btlr
Name: interferon gamma receptor 1; mutation 1, Bruce Beutler
MGI ID: MGI:5806453
Synonyms: marigold
Gene: Ifngr1  Location: Chr10:19467697-19485977 bp, + strand  Genetic Position: Chr10, 8.49 cM
Alliance: Ifngr1m1Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced T to C transition at base pair 19,601,485 (v38) on chromosome 10, or base pair 9,528 in the GenBank genomic region NC_000076 within the donor splice site of intron 3. The effects of the mutation at the cDNA and protein level have not examined, but the mutation could result in skipping of the 164-nucleotide exon 3 (out of 7 total exons). Deletion of exon 3 would result in a frame-shift and coding of 24 aberrant amino acids followed by a premature stop codon after amino acid 100. (J:236694)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ifngr1 Mutation:  53 strains or lines available
References
Original:  J:236694 Sun L, et al., Mutagenetix entry for marigold. MGI Direct Data Submission. 2016;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory