Nalcn^em1Iiis
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nalcn^em1Iiis
• Name: sodium leak channel, non-selective; endonuclease-mediated mutation 1, Masashi Yanagisawa and Hiromasa Funato
• MGI ID: MGI:5806546
• Synonyms: CRISPR Nalcn^Drl, Nalcn^em1Staka
• Gene: Nalcn Location: Chr14:123514046-123864556 bp, - strand Genetic Position: Chr14, 66.04 cM
• Alliance: Nalcn^em1Iiis page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR/Cas technology introduced A to T substitution that results in an amino acid substitution at the 315th residue from asparagine to lysine (N315K) replicating Nalcn^Drl. (J:236598)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nalcn Mutation: 116 strains or lines available

References

• Original: J:236598 Funato H, et al., Forward-genetics analysis of sleep in randomly mutagenized mice. Nature. 2016 Nov 17;539(7629):378-383
• All: 1 reference(s)