Kdm4c^Gt(897)Tgen
Gene trapped Allele Detail

Summary

• Symbol: Kdm4c^Gt(897)Tgen
• Name: lysine (K)-specific demethylase 4C; gene trap 897, TransGenic
• MGI ID: MGI:5806952
• Gene: Kdm4c Location: Chr4:74160734-74324097 bp, + strand Genetic Position: Chr4, 36.06 cM
• Alliance: Kdm4c^Gt(897)Tgen page

Mutation origin

• Mutant Cell Line: 897
• Germline Transmission: Earliest citation of germline transmission: J:227280
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pU-17 Vector Type: gene trap
• Mutation details: The gene trap vector inserted begtween exon 1 and 2. Western blot analysis confirmed reduced protein expression in mouse embryonic fibroblasts from heterozygous mice. (J:227280)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm4c Mutation: 372 strains or lines available

References

• Original: J:227280 Ozaki Y, et al., The oncogenic role of GASC1 in chemically induced mouse skin cancer. Mamm Genome. 2015 Dec;26(11-12):591-7
• All: 2 reference(s)