Pbrm1^tm1Zhwa
Targeted Allele Detail

Summary

• Symbol: Pbrm1^tm1Zhwa
• Name: polybromo 1; targeted mutation 1, Zhong Wang
• MGI ID: MGI:5810066
• Synonyms: BAF180^fl, Pbrm1^tm1.1Zhwa
• Gene: Pbrm1 Location: Chr14:30741095-30843549 bp, + strand Genetic Position: Chr14, 19.09 cM, cytoband B
• Alliance: Pbrm1^tm1Zhwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236906
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A targeting vector is designed to insert a single loxP site upstream of exon 11, and an FRT-flanked betageo cassette, followed by a loxP site, downstream of exon 11. (J:236906)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pbrm1 Mutation: 90 strains or lines available

References

• Original: J:236906 Wurster AL, et al., IL-10 transcription is negatively regulated by BAF180, a component of the SWI/SNF chromatin remodeling enzyme. BMC Immunol. 2012 Feb 15;13:9
• All: 9 reference(s)