Gtf2i^tm1.1Bdash
Targeted Allele Detail

Summary

• Symbol: Gtf2i^tm1.1Bdash
• Name: general transcription factor II I; targeted mutation 1.1, Dashzeveg Bayarsaihan
• MGI ID: MGI:5810123
• Synonyms: Grf2i^fl
• Gene: Gtf2i Location: Chr5:134266688-134343614 bp, - strand Genetic Position: Chr5, 74.48 cM
• Alliance: Gtf2i^tm1.1Bdash page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236328
• Parent Cell Line: D2 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-site flanked PGKneo selection cassette containing was inserted downstream of exon 3 of the targeted gene, and another loxP site was inserted upstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 3 floxed. (J:236328)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gtf2i Mutation: 139 strains or lines available

References

• Original: J:236328 Enkhmandakh B, et al., Generation of a mouse model for a conditional inactivation of Gtf2i allele. Genesis. 2016 Jul;54(7):407-12
• All: 5 reference(s)