Aipl1^tvrm119
Chemically induced Allele Detail

Summary

• Symbol: Aipl1^tvrm119
• Name: aryl hydrocarbon receptor-interacting protein-like 1; translational vision research model 119
• MGI ID: MGI:5810589
• Gene: Aipl1 Location: Chr11:71918789-71928335 bp, - strand Genetic Position: Chr11, 43.81 cM
• Alliance: Aipl1^tvrm119 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: This ENU-induced c.276+5G>A single nucleotide transition in a splice donor site is predicted to delete expression of exon 2 and thereby result in an in-frame deletion of amino acids Val33-Ile92, which includes much of the FKBP homology domain. (J:243745)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aipl1 Mutation: 30 strains or lines available

References

• Original: J:243745 Krebs MP, et al., Mouse models of human ocular disease for translational research. PLoS One. 2017;12(8):e0183837
• All: 2 reference(s)