Rho^Tvrm334
Chemically induced Allele Detail

Summary

• Symbol: Rho^Tvrm334
• Name: rhodopsin; translational research vision model 334
• MGI ID: MGI:5810761
• Gene: Rho Location: Chr6:115908709-115916997 bp, + strand Genetic Position: Chr6, 53.72 cM
• Alliance: Rho^Tvrm334 page

Mutation origin

• Strain of Origin: B6.Cg-Crb1^rd8/Pjn

Mutation description

• Allele Type: Chemically induced (ENU) (Humanized sequence)
• Mutation: Single point mutation
• Mutation details: This ENU induced c.533A>G point transition leads to a Tyr178Cys substitution in the intradiscal region. (J:243745)
• Inheritance: Dominant

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rho Mutation: 51 strains or lines available

References

• Original: J:243745 Krebs MP, et al., Mouse models of human ocular disease for translational research. PLoS One. 2017;12(8):e0183837
• All: 2 reference(s)