Alms1^tvrm102
Chemically induced Allele Detail

Summary

• Symbol: Alms1^tvrm102
• Name: ALMS1, centrosome and basal body associated; translational vision research model 102
• MGI ID: MGI:5810779
• Gene: Alms1 Location: Chr6:85564513-85679735 bp, + strand Genetic Position: Chr6, 37.48 cM
• Alliance: Alms1^tvrm102 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: This ENU-induced T>C point transition (c. 1080+2 T>C) in the exon 6 splice donor site that unmasks a cryptic splice site 120 bases downstream. (J:243745)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Alms1 Mutation: 150 strains or lines available

References

• Original: J:243745 Krebs MP, et al., Mouse models of human ocular disease for translational research. PLoS One. 2017;12(8):e0183837
• All: 3 reference(s)