Gpr84^del
Spontaneous Allele Detail

Summary

• Symbol: Gpr84^del
• Name: G protein-coupled receptor 84; deletion
• MGI ID: MGI:5812913
• Gene: Gpr84 Location: Chr15:103216662-103219039 bp, - strand Genetic Position: Chr15, 58.88 cM
• Alliance: Gpr84^del page

Mutation origin

• Strain of Origin: multiple strains

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This spontaneously arising frameshift deletion is located in exon 2 at position 103308576 bp (NCBI Build 37) and results in a premature stop codon. The mutation is predicted to result in a truncated protein lacking the transmembrane domains 4-7. The inbred strains BDP/J, DBA/1J, DBA/2J, I/LnJ, FVB/NJ, LG/J, MRL/MpJ, NODShi/LtJ, NOR/LtJ, P/J, PL/J, SKHIN/Sprd, SJL/J, SM/J are homozygous for the deletion. The allele is segregating in the outbred stocks ICR and CD-1. (J:237405)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 15 strains available Cell Lines: 0 lines available
• Carrying any Gpr84 Mutation: 33 strains or lines available

References

• Original: J:237405 Perez CJ, et al., Several classical mouse inbred strains, including DBA/2, NOD/Lt, FVB/N, and SJL/J, carry a putative loss-of-function allele of Gpr84. J Hered. 2013 Jul-Aug;104(4):565-71
• All: 4 reference(s)