Scube3^m1Mhda
Chemically induced Allele Detail

Summary

• Symbol: Scube3^m1Mhda
• Name: signal peptide, CUB domain, EGF-like 3; mutation 1, Martin Hrabe de Angelis
• MGI ID: MGI:5817460
• Synonyms: KTA041, Scube3^Mhdakta041, Scube3^N294K, Scube3^N294KMhda
• Gene: Scube3 Location: Chr17:28361115-28393828 bp, + strand Genetic Position: Chr17, 14.63 cM
• Alliance: Scube3^m1Mhda page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: A C-to-A transversion at nucleotide position 882 in exon 8 leads to an asparagine to lysine exchange at protein position 294 (N294K). (J:237904)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

23 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Scube3 Mutation: 47 strains or lines available

Notes

Phenotypic Similarity to Human Syndrome: Paget disease of the bone 1 J: 237904.

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 3 reference(s)