Il22ra1^tm1.1Koll
Targeted Allele Detail

Summary

• Symbol: Il22ra1^tm1.1Koll
• Name: interleukin 22 receptor, alpha 1; targeted mutation 1.1, Jay K Kolls
• MGI ID: MGI:5817816
• Synonyms: Il22ra1^fl
• Gene: Il22ra1 Location: Chr4:135455483-135479451 bp, + strand Genetic Position: Chr4, 67.99 cM
• Alliance: Il22ra1^tm1.1Koll page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237979
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT flanked neomycin resistance cassette with a loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and leaves exon 3 floxed. (J:237979)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Il22ra1 Mutation: 31 strains or lines available

References

• Original: J:237979 Zheng M, et al., Therapeutic Role of Interleukin 22 in Experimental Intra-abdominal Klebsiella pneumoniae Infection in Mice. Infect Immun. 2016 Jan 04;84(3):782-9
• All: 7 reference(s)