Nlrp12^C57BL/6J
Spontaneous Allele Detail

Summary

• Symbol: Nlrp12^C57BL/6J
• Name: NLR family, pyrin domain containing 12; C57BL/6J
• MGI ID: MGI:5817983
• Synonyms: Nlrp12^B6J
• Gene: Nlrp12 Location: Chr7:3267458-3298370 bp, - strand Genetic Position: Chr7, 1.88 cM
• Alliance: Nlrp12^C57BL/6J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous (Not Applicable)
• Mutation: Single point mutation
• Mutation details: A sequence variant is identified in C57BL/6J (T) as compared to C57BL/6N (C) at position 3,222,537 (GRCm38). The polymorphism is located in the C-terminal leucine-rich repeat domain and results in an arginine to lysine change at amino acid residue 1034 (p.R1034K). (J:220417)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nlrp12 Mutation: 51 strains or lines available

References

• Original: J:220417 Simon MM, et al., A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biol. 2013;14(7):R82
• All: 14 reference(s)