Foxg1^{tm1.1(cre)Ddmo}
Targeted Allele Detail

Summary

• Symbol: Foxg1^{tm1.1(cre)Ddmo}
• Name: forkhead box G1; targeted mutation 1.1, Dennis D M O'Leary
• MGI ID: MGI:5818697
• Synonyms: Foxg1-IRES-Cre
• Gene: Foxg1 Location: Chr12:49429666-49433650 bp, + strand Genetic Position: Chr12, 21.78 cM
• Alliance: Foxg1^{tm1.1(cre)Ddmo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231606
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129T/Sv

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Foxg1^{tm1.1(cre)Ddmo} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Foxg1 (MGI:1347464)

• Mutation details: An IRES-cre gene followed by an frt-flanked PGK-neo was inserted at 27bp downstream of the stop codon of the gene by homologous recombination in ES cells. Resulting mice were crossed with FLPe expressing mice to remove the PGK-neo cassette. (J:231606)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxg1 (mouse) Summary of all recombinase alleles driven by Foxg1. Alliance mouse Foxg1 gene page

Expression

In Mice Carrying this Mutation:

40 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxg1 Mutation: 29 strains or lines available

References

• Original: J:231606 Kawaguchi D, et al., Generation and analysis of an improved Foxg1-IRES-Cre driver mouse line. Dev Biol. 2016 Apr 1;412(1):139-47
• All: 19 reference(s)