Osbpl5em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Osbpl5em1(IMPC)J |
Name: |
oxysterol binding protein-like 5; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:5818708 |
Synonyms: |
Osbpl5em1J |
Gene: |
Osbpl5 Location: Chr7:143242499-143310722 bp, - strand Genetic Position: Chr7, 88.29 cM
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Alliance: |
Osbpl5em1(IMPC)J page
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IMPC: |
Osbpl5 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele from project Osbpl5-8180J-F0511 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TCTCAAACTGCAGAGCCAGG, AGTGAGAGAGTCACACAAAT, GGTGGCCCCGAAGAGTGAGG and TCAGACCTCATCTAAGGCTA, which resulted in a 309 bp deletion beginning at Chromosome 7 negative strand position 143715937 bp, CTCACTCTTCGGGGCCACCT, and ending after GGATCTGGGGTCCTCCTGGC at 143,715,629 bp (GRCm38/mm10). This mutation deletes exon 2 and 152 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 17 and early truncation 75 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
2 reference(s) |
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