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Cd83tm1.1Lnjt
Targeted Allele Detail
Summary
Symbol: Cd83tm1.1Lnjt
Name: CD83 antigen; targeted mutation 1.1, Lars Nitschke
MGI ID: MGI:5819103
Synonyms: cd83fl
Gene: Cd83  Location: Chr13:43938661-43956608 bp, + strand  Genetic Position: Chr13, 21.6 cM, cytoband A4-5
Alliance: Cd83tm1.1Lnjt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:238327
Parent Cell Line:  JM8A3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsExons 1 and 2 of the gene were flanked with two loxP sites. The frt-flanked neomycin resistance cassette was removed by mating to Flp recombinase expressing mice. (J:238327)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd83 Mutation:  17 strains or lines available
References
Original:  J:238327 Krzyzak L, et al., CD83 Modulates B Cell Activation and Germinal Center Responses. J Immunol. 2016 May 01;196(9):3581-94
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory