Vit^tm1Koth
Targeted Allele Detail

Summary

• Symbol: Vit^tm1Koth
• Name: vitrin; targeted mutation 1, Kunimasa Ohta
• MGI ID: MGI:5823247
• Synonyms: AKH^-
• Gene: Vit Location: Chr17:78815493-78934837 bp, + strand Genetic Position: Chr17, 49.38 cM, cytoband E3
• Alliance: Vit^tm1Koth page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237454
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A loxP-flanked neomycin selection cassette was inserted into the single coding exon of the gene. (J:237454)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vit Mutation: 51 strains or lines available

References

• Original: J:237454 Abdulhaleem FA, et al., Akhirin regulates the proliferation and differentiation of neural stem cells in intact and injured mouse spinal cord. Dev Neurobiol. 2015 May;75(5):494-504
• All: 2 reference(s)