Tg(CD2-S1PR1)1Ejg
Transgene Detail

Summary

• Symbol: Tg(CD2-S1PR1)1Ejg
• Name: transgene insertion 1, Edward J Goetzl
• MGI ID: MGI:5824062
• Synonyms: S1pr1-Tg, S1P^sub1^/subR-Tg
• Transgene: Tg(CD2-S1PR1)1Ejg Location: unknown
• Alliance: Tg(CD2-S1PR1)1Ejg page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD2-S1PR1)1Ejg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  S1PR1 (1901)

  S1pr1

  (MGI:1096355)

• Mutation details: The transgenic construct was designed with the coding region of the human sphingosine-1-phosphate receptor 1 (S1PR1) gene driven by the human CD2 antigen promoter/enhancer sequences. (J:96558)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:96558 Graler MH, et al., Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes. J Immunol. 2005 Feb 15;174(4):1997-2003
• All: 2 reference(s)