Tg(Erbb2-Erbb2)NN60Led
Transgene Detail

Summary

• Symbol: Tg(Erbb2-Erbb2)NN60Led
• Name: transgene insertion NN60, Philip Leder
• MGI ID: MGI:5824244
• Transgene: Tg(Erbb2-Erbb2)NN60Led Location: unknown
• Alliance: Tg(Erbb2-Erbb2)NN60Led page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Erbb2-Erbb2)NN60Led expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Erbb2 (24337)

  Erbb2

  (MGI:95410)

• Mutation details: This transgene expresses the rat wild-type Erbb2 (neu) cDNA under the control of the mouse Erbb2 (neu) promoter. This line contains only a single copy of the transgene. RT-PCR confirmed transgene expression in the ovary, lung, heart, and testis, but not in the liver or kidney. (J:62441)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:62441 Weinstein EJ, et al., A mouse model for breast cancer induced by amplification and overexpression of the neu promoter and transgene. Mol Med. 2000 Jan;6(1):4-16
• All: 1 reference(s)