Tg(BAC144D14)5D3Masu
Transgene Detail

Summary

• Symbol: Tg(BAC144D14)5D3Masu
• Name: transgene insertion 5D3, M Azim Surani
• MGI ID: MGI:5825057
• Synonyms: BACx1
• Transgene: Tg(BAC144D14)5D3Masu Location: unknown
• Alliance: Tg(BAC144D14)5D3Masu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(BAC144D14)5D3Masu expresses 4 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cdkn1c (MGI:104564)
  mouse	Nap1l4 (MGI:1316687)
  mouse	Phlda2 (MGI:1202307)
  mouse	Slc22a18 (MGI:1336884)

• Mutation details: This transgene consists of BAC clone 144D14 from Genome Systems that covers 60 kb of sequence upstream of Cdkn1c and 25 kb of sequence downstream of Cdkn1c. The BAC also contains Slc22a18, Phlda2, and exon 15 of Nap1l4 but not the 3' UTR of Kcnq1 which lies about 30 kb downstream of Cdkn1c. Three lines were established; 5D3, 5B6, and 5A2. This is the 1 copy number line. (J:70843)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:70843 John RM, et al., Distant cis-elements regulate imprinted expression of the mouse p57( Kip2) (Cdkn1c) gene: implications for the human disorder, Beckwith-Wiedemann syndrome. Hum Mol Genet. 2001 Jul 15;10(15):1601-9
• All: 4 reference(s)