Fbxo10em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Fbxo10em1(IMPC)J |
Name: |
F-box protein 10; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:5827555 |
Synonyms: |
Fbxo10em1J |
Gene: |
Fbxo10 Location: Chr4:45034248-45084555 bp, - strand Genetic Position: Chr4, 23.68 cM
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Alliance: |
Fbxo10em1(IMPC)J page
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IMPC: |
Fbxo10 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele from project Fbxo10- 8390J-M4753 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GTAATCTCCCGAGGAGCAGG, AGTGCCAGATAGTCTGGGCA, GTACCAAGACGGACACAGCC and GCTGTGTGCTCAGGAATGGC, which resulted in a 512 bp deletion beginning at Chromosome 4 positive strand position 45,048,176 bp, GGAGGCACATGGTTGCCTTT, and ending after AGGACAAAACACCACCAGCC at 45,048,687 bp (GRCm38/mm10). This mutation deletes exon 5 and 375 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 519 and early truncation 28 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
3 reference(s) |
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