Del(5Kit-Nmu)2Utr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(5Kit-Nmu)2Utr
• Name: deletion, Chr 5, Ken-ichi Yagami 2
• MGI ID: MGI:5828636
• Synonyms: Del2Staka, Del(5Kit-Nmu)2Staka, Kit^WE
• Gene: Del(5Kit-Nmu)2Utr Location: unknown Genetic Position: Chr5, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(5Kit-Nmu)2Utr involves 26 genes/genome features (Gm24738, Gm25374, Gm33832 ...) View all
• Mutation details: CRISPR/Cas technology targeted a region 240 kb upstream of Kit and 81 kb downstream of Nmu to generate a 1.07 Mb deletion including several genes. The left CRISPR target site was located on Chr. 5: 75,408,45975,408,481 and the right target site was located on Chr. 5: 76,444,36176,444,383 (Build GRCm38). (J:233978)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(5Kit-Nmu)2Utr Mutation: 0 strains or lines available

References

• Original: J:233978 Mizuno S, et al., Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation. Sci Rep. 2015;5:13632
• All: 1 reference(s)