Baiap2l1^tm1Zgh
Targeted Allele Detail

Summary

• Symbol: Baiap2l1^tm1Zgh
• Name: BAI1-associated protein 2-like 1; targeted mutation 1, Ze-Guang Han
• MGI ID: MGI:5828650
• Synonyms: IRTKS-KO
• Gene: Baiap2l1 Location: Chr5:144201336-144294922 bp, - strand Genetic Position: Chr5, 83.24 cM
• Alliance: Baiap2l1^tm1Zgh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238622
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exon 1. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts and liver. (J:238622)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Baiap2l1 Mutation: 46 strains or lines available

References

• Original: J:238622 Huang LY, et al., Deficiency of IRTKS as an adaptor of insulin receptor leads to insulin resistance. Cell Res. 2013 Nov;23(11):1310-21
• All: 2 reference(s)