Ank3^tm3Bnt
Targeted Allele Detail

Summary

• Symbol: Ank3^tm3Bnt
• Name: ankyrin 3, epithelial; targeted mutation 3, Vann Bennett
• MGI ID: MGI:5829748
• Gene: Ank3 Location: Chr10:69234608-69863266 bp, + strand Genetic Position: Chr10, 36.1 cM
• Alliance: Ank3^tm3Bnt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218905
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was placed in intron 36 and an FRT-loxP-neomycin-FRT-loxP cassette was introduced to intron 37 via homologous recombination. (J:218905)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ank3 Mutation: 170 strains or lines available

References

• Original: J:218905 Jenkins PM, et al., Giant ankyrin-G: A critical innovation in vertebrate evolution of fast and integrated neuronal signaling. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):957-64
• All: 1 reference(s)