Foxc2^tm1.1Miu
Targeted Allele Detail

Summary

• Symbol: Foxc2^tm1.1Miu
• Name: forkhead box C2; targeted mutation 1.1, Naoyuki Miura
• MGI ID: MGI:5882729
• Synonyms: Foxc2^fl
• Gene: Foxc2 Location: Chr8:121842910-121845634 bp, + strand Genetic Position: Chr8, 70.33 cM
• Alliance: Foxc2^tm1.1Miu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226391
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The coding exon was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the coding exon. (J:226391, J:316530)

Expression

In Mice Carrying this Mutation:	23 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxc2 Mutation: 15 strains or lines available

References

• Original: J:226391 Sabine A, et al., FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature. J Clin Invest. 2015 Oct 1;125(10):3861-77
• All: 7 reference(s)