Btbd18^tm1Dean
Targeted Allele Detail

Summary

• Symbol: Btbd18^tm1Dean
• Name: BTB domain containing 18; targeted mutation 1, Jurrien Dean
• MGI ID: MGI:5888779
• Synonyms: Btbd18^Null
• Gene: Btbd18 Location: Chr2:84489423-84499124 bp, + strand Genetic Position: Chr2, 49.45 cM
• Alliance: Btbd18^tm1Dean page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240025
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 5, which contains most of the gene coding sequence, was replaced with a loxP-flanked neomycin selection cassette. (J:240025)

Expression

In Mice Carrying this Mutation:	16 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Btbd18 Mutation: 18 strains or lines available

References

• Original: J:240025 Zhou L, et al., BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice. Dev Cell. 2017 Mar 13;40(5):453-466.e5
• All: 1 reference(s)