Oxtr^{tm1.1(cre/GFP)Rpa}
Targeted Allele Detail

Summary

• Symbol: Oxtr^{tm1.1(cre/GFP)Rpa}
• Name: oxytocin receptor; targeted mutation 1.1, Richard D Palmiter
• MGI ID: MGI:5896317
• Gene: Oxtr Location: Chr6:112450644-112466904 bp, - strand Genetic Position: Chr6, 52.27 cM, cytoband E3
• Alliance: Oxtr^{tm1.1(cre/GFP)Rpa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutation: Insertion
• Oxtr^{tm1.1(cre/GFP)Rpa} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Oxtr (MGI:109147)

• Mutation details: IRES-Myc tag-nuclear localization signal (NLS)-cre-GFP-frt-neomycin-frt were introduced just after the termination codon of the mouse Oxtr gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Oxtr (mouse) Summary of all recombinase alleles driven by Oxtr. Alliance mouse Oxtr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oxtr Mutation: 41 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 3 reference(s)